First Publication – We are expanding into Nanobody Engineering
Our collaboration with Prof. Dr. Harald Kolmar's research group at Technische Universität Darmstadt together with Felix Geyer has resulted in a publication in Antibodies MDPI showing an innovative advancement in nanobody engineering, by combing ML-based tools and rational design principles:
https://doi.org/10.3390/antib14030073
With our part: a free and public nanobody aggregation score pipeline avaliable on the xyna.bio platform.
And we are just getting started. Together with TU Darmstadt, we are developing neurosymbolic models that combine domain specific expert knowledge, fine tuned ML-based tools (Boltz2, ProteinGPTs, diffusion models), symbolic AI, with biophysical-chemical-mathematical models in ensemble predictions orchestrated by agents, intelligently controling model combinations, parametrization and more.
This milestone demonstrates how interdisciplinary research drives innovation. The future is created where AI, biotechnology, and interdisciplinary excellence converge - here at xyna.bio.
A big thank you for this amazing work to Felix Geyer and the entire Kolmar Group, as well as to the whole xyna.bio Team, specifically Wiktoria Palka, Julian Borbeck, Annika Bamberger, Jan Luca Metzler, and the development team led by Sebastian B.!
